Unveiling the Silent Specter: COVID-19 and the Hidden Crisis of Brain Inflammation

Roy Cohen
3 min readApr 29, 2024

Hello, fellow science enthusiasts and concerned citizens of the globe! I’m Roy Cohen, a neuroscientist, mental health advocate, and, given the current climate, a somewhat reluctant amateur virologist (I was always a germaphobe, there, I’ve said it). As the CEO of Behavidence, where we dive deep into the realm of digital biomarkers for mental health, I’ve been at the intersection of technology, neuroscience, and now, epidemiology — thanks to our uninvited guest, COVID-19.

In the myriad of discussions surrounding the, now seems historic, pandemic — ranging from toilet paper shortages to the debates over mask aesthetics — there’s a crucial topic that’s been largely overlooked by the media: brain inflammation following COVID infections. Yes, while everyone has been busy sanitizing their groceries (admit it, you’ve done it too), the silent specter of neurological after-effects has been haunting a significant portion of the population.

In my close relatives and patients’ environment I’ve seen everything from memory loss, CT scans that look like a flood of inflamed white matter, and even several fatal intracranial hemorrhages. Now I don’t want to point fingers, but it’s time someone does, Isn’t it?

Recent studies have illuminated some startling connections. COVID-19 isn’t just a respiratory nuisance; it plays a rather sinister game with our brains. Research indicates a correlation between COVID-19 infections and elevated brain inflammatory markers. These aren’t just fleeting changes; they are linked to long-term neurological disorders such as depression, PTSD, migraines, and the ever-elusive brain fog that many dismiss as just another Monday morning feeling ([1],[2]). But wait, there’s more — reports are surfacing of Alzheimer-like symptoms ([3]) and even Parkinson’s disease in post-COVID patients ([4]).
(I’m throwing another link to the mystery of Covid-19 and intracranial hemorrhage here as well, if you’re like me, looking for reasons to panic: ([5])

From https://www.itnonline.com/content/mri-reveals-significant-brain-abnormalities-post-covid

Now, while our societal approach to recovery has been akin to fixing a leaky faucet with a wad of gum — temporary and superficial — the real issue at hand demands a robust biological research initiative and a strategic intervention plan. It’s not enough to treat the psychiatric symptoms as they surface; that’s like mopping the floor while the sink overflows.

The focus has largely been on vaccinations and herd immunity — a fantastic display of scientific prowess and community effort, no doubt. However, as we pat ourselves on the back for these achievements, the underbelly of the pandemic effects continues to grow, largely unaddressed.

What we need is a shift in narrative and priorities. It’s time to pull our heads out of the sand (or perhaps out of the virology textbooks) and take a good hard look at the neuroinflammatory processes that could be affecting millions. We’re not just dealing with a virus; we’re up against a potential wave of neurodegenerative conditions that could reshape the landscape of public health.

So, as we continue to adapt to this new world, let’s make sure we’re not just surviving, but actively preparing to tackle the after-effects that could ripple through our healthcare systems for years to come. And hey, maybe while we’re at it, let’s keep the humor alive — because if we can’t laugh at the absurdity of chasing after toilet paper like it’s the last chopper out of ‘Nam, then, my friends, the virus has already won.

Stay safe, stay informed, and let’s tackle this hidden crisis together — not just as survivors, but as pioneers of a new understanding in post-pandemic healthcare.

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Roy Cohen

Co-Founder and CEO at Behavidence, Inc. A mad scientist, but the type you want to meet on the street.